The Irish Script on Screen project was launched in 1999 under the direction of Pádraig Ó Macháin. In its early years it operated in collaboration with the School of Computer Applications at Dublin City University. In addition to contributing to the funding of the project, DCU, under the supervision of Professor Alan Smeaton, provided the necessary technical expertise in digital processing and storage.

The project has also benefited from the generosity of the Irish Heritage Council.

Over the years many talented people have worked with us on the digitisation and processing of images of Irish manuscripts: Catherine Moran, Criostaí Mac Íomhaire, Evan Lloyd, David Cooper, Máire Casey, Georgina Gaughan, Colin Dunn, John O'Brien, and currently Anne Marie O’Brien.

Since 2004, Irish Script on Screen has operated solely as a project of the Dublin Institute for Advanced Studies.